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- 宋峻杰
- 周惠民、李凱婷
- 陳茹玲、曾厚強、林慶隆、宋曜廷、柯華葳
A systematic review of multisensory cognitive–affective integration in schizophrenia
The etymology of schizophrenia implies poor functional integration of sensory, cognitive and affective processes. Multisensory integration (MSI) is a spontaneous perceptual–cognitive process by which relevant information from multiple sensory modalities is extracted to generate a holistic experience. Deficits in MSI may hinder prompt and appropriate behavioural responses in a complex and transient environment. Despite extensive investigation of sensory, cognitive and affective processing in patients with schizophrenia, little is known about how MSI is affected in the illness. We systemically searched the PubMed electronic database and reviewed twenty-nine behavioural and neuroimaging studies examining MSI in patients with schizophrenia. The available evidence indicates impaired MSI for non-emotional stimuli in schizophrenia, especially for linguistic information. There is also evidence for altered MSI for emotional stimuli, although findings are inconsistent and may be modality-specific. Brain functional alterations in the superior temporal cortex and inferior frontal cortex appear to underlie the deficits in both non-emotional and emotional MSI. The limitations of the experimental paradigms used and directions for future research are also discussed.
曾懷萱、陳冠銘- 李源順、吳正新、林吟霞、李哲迪
- 洪詠善、陳木金、盧秋珍
- 洪詠善、吳敏而
- 林慶隆、彭致翎、吳培若
- 林慶隆、陳昀萱、林信成